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DSP Crosslinker
CAS No. 57757-57-0
DSP Crosslinker( —— )
Catalog No. M24569 CAS No. 57757-57-0
DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 50 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDSP Crosslinker
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NoteResearch use only, not for human use.
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Brief DescriptionDSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
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DescriptionDSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
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In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorCleavable
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Research Area——
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Indication——
Chemical Information
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CAS Number57757-57-0
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Formula Weight404.42
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Molecular FormulaC14H16N2O8S2
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Purity>98% (HPLC)
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SolubilityDMSO:90mg/ml(222.54mM; Need ultrasonic)
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SMILESO=C(CCSSCCC(ON(C(CC1)=O)C1=O)=O)ON(C(CC1)=O)C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zorea J, et al. Probing antibody surface density and analyte antigen incubation time as dominant parameters influencing the antibody-antigen recognition events of a non-faradaic and diffusion-restricted electrochemical immunosensor. Anal Bioanal Chem. 2020 Mar;412(7):1709-1717.
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DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins.
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DBCO acid 3
DBCO acid 3 is a Click Chemistry intermidate used for antibody-drug conjugates.
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DBCO intermidate 3
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